Treatment of Metabolic syndrome by combination of physical activity and diet needs an optimal protein intake: a randomized controlled trial
Identifieur interne : 005225 ( Main/Exploration ); précédent : 005224; suivant : 005226Treatment of Metabolic syndrome by combination of physical activity and diet needs an optimal protein intake: a randomized controlled trial
Auteurs : Frédéric Dutheil [France] ; Gérard Lac [France] ; Daniel Courteix [France, Australie] ; Eric Doré [France] ; Robert Chapier [France] ; Laurence Roszyk [France] ; Vincent Sapin [France] ; Bruno Lesourd [France]Source :
- Nutrition Journal [ 1475-2891 ] ; 2012.
Abstract
The recommended dietary allowance (RDA) for protein intake has been set at 1.0-1.3 g/kg/day for senior. To date, no consensus exists on the lower threshold intake (LTI = RDA/1.3) for the protein intake (PI) needed in senior patients ongoing both combined caloric restriction and physical activity treatment for metabolic syndrome. Considering that age, caloric restriction and exercise are three increasing factors of protein need, this study was dedicated to determine the minimal PI in this situation, through the determination of albuminemia that is the blood marker of protein homeostasis.
Twenty eight subjects (19 M, 9 F, 61.8 ± 6.5 years, BMI 33.4 ± 4.1 kg/m2) with metabolic syndrome completed a three-week residential programme (Day 0 to Day 21) controlled for nutrition (energy balance of −500 kcal/day) and physical activity (3.5 hours/day). Patients were randomly assigned in two groups: Normal-PI (NPI: 1.0 g/kg/day) and High-PI (HPI: 1.2 g/kg/day). Then, patients returned home and were followed for six months. Albuminemia was measured at D0, D21, D90 and D180.
At baseline, PI was spontaneously 1.0 g/kg/day for both groups. Albuminemia was 40.6 g/l for NPI and 40.8 g/l for HPI. A marginal protein under-nutrition appeared in NPI with a decreased albuminemia at D90 below 35 g/l (34.3 versus 41.5 g/l for HPI, p < 0.05), whereas albuminemia remained stable in HPI.
During the treatment based on restricted diet and exercise in senior people with metabolic syndrome, the lower threshold intake for protein must be set at 1.2 g/kg/day to maintain blood protein homeostasis.
Url:
DOI: 10.1186/1475-2891-11-72
PubMed: 22985437
PubMed Central: 3502154
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001656
- to stream Pmc, to step Curation: 001516
- to stream Pmc, to step Checkpoint: 001D31
- to stream Ncbi, to step Merge: 000F80
- to stream Ncbi, to step Curation: 000F80
- to stream Ncbi, to step Checkpoint: 000F80
- to stream Main, to step Merge: 005424
- to stream Main, to step Curation: 005225
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Treatment of Metabolic syndrome by combination of physical activity and diet needs an optimal protein intake: a randomized controlled trial</title><author><name sortKey="Dutheil, Frederic" sort="Dutheil, Frederic" uniqKey="Dutheil F" first="Frédéric" last="Dutheil">Frédéric Dutheil</name><affiliation wicri:level="1"><nlm:aff id="I1">Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I2">Sport Medicine and Functional Explorations, University Hospital (CHU) G. Montpied, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Sport Medicine and Functional Explorations, University Hospital (CHU) G. Montpied, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I3">Occupational Medicine, Faculty of Medicine, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Occupational Medicine, Faculty of Medicine, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation></author><author><name sortKey="Lac, Gerard" sort="Lac, Gerard" uniqKey="Lac G" first="Gérard" last="Lac">Gérard Lac</name><affiliation wicri:level="1"><nlm:aff id="I1">Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation></author><author><name sortKey="Courteix, Daniel" sort="Courteix, Daniel" uniqKey="Courteix D" first="Daniel" last="Courteix">Daniel Courteix</name><affiliation wicri:level="1"><nlm:aff id="I1">Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I6">School of Exercise Science, Australian Catholic University, Locked Bag 4115 Fitzroy MDC VIC 3165, , Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Exercise Science, Australian Catholic University, Locked Bag 4115 Fitzroy MDC VIC 3165, </wicri:regionArea><wicri:noRegion></wicri:noRegion></affiliation></author><author><name sortKey="Dore, Eric" sort="Dore, Eric" uniqKey="Dore E" first="Eric" last="Doré">Eric Doré</name><affiliation wicri:level="1"><nlm:aff id="I1">Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation></author><author><name sortKey="Chapier, Robert" sort="Chapier, Robert" uniqKey="Chapier R" first="Robert" last="Chapier">Robert Chapier</name><affiliation wicri:level="1"><nlm:aff id="I1">Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation></author><author><name sortKey="Roszyk, Laurence" sort="Roszyk, Laurence" uniqKey="Roszyk L" first="Laurence" last="Roszyk">Laurence Roszyk</name><affiliation wicri:level="1"><nlm:aff id="I5">Biochemistry, University Hospital (CHU) G. Montpied, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Biochemistry, University Hospital (CHU) G. Montpied, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation></author><author><name sortKey="Sapin, Vincent" sort="Sapin, Vincent" uniqKey="Sapin V" first="Vincent" last="Sapin">Vincent Sapin</name><affiliation wicri:level="1"><nlm:aff id="I5">Biochemistry, University Hospital (CHU) G. Montpied, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Biochemistry, University Hospital (CHU) G. Montpied, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation></author><author><name sortKey="Lesourd, Bruno" sort="Lesourd, Bruno" uniqKey="Lesourd B" first="Bruno" last="Lesourd">Bruno Lesourd</name><affiliation wicri:level="1"><nlm:aff id="I1">Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">Geriatrics Departments, Faculty of Medicine, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Geriatrics Departments, Faculty of Medicine, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">22985437</idno><idno type="pmc">3502154</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502154</idno><idno type="RBID">PMC:3502154</idno><idno type="doi">10.1186/1475-2891-11-72</idno><date when="2012">2012</date><idno type="wicri:Area/Pmc/Corpus">001656</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001656</idno><idno type="wicri:Area/Pmc/Curation">001516</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">001516</idno><idno type="wicri:Area/Pmc/Checkpoint">001D31</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">001D31</idno><idno type="wicri:Area/Ncbi/Merge">000F80</idno><idno type="wicri:Area/Ncbi/Curation">000F80</idno><idno type="wicri:Area/Ncbi/Checkpoint">000F80</idno><idno type="wicri:Area/Main/Merge">005424</idno><idno type="wicri:Area/Main/Curation">005225</idno><idno type="wicri:Area/Main/Exploration">005225</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Treatment of Metabolic syndrome by combination of physical activity and diet needs an optimal protein intake: a randomized controlled trial</title><author><name sortKey="Dutheil, Frederic" sort="Dutheil, Frederic" uniqKey="Dutheil F" first="Frédéric" last="Dutheil">Frédéric Dutheil</name><affiliation wicri:level="3"><nlm:aff id="I1">Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand</wicri:regionArea><placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region><region type="old region" nuts="2">Auvergne (région administrative)</region><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="I2">Sport Medicine and Functional Explorations, University Hospital (CHU) G. Montpied, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Sport Medicine and Functional Explorations, University Hospital (CHU) G. Montpied, F-63000, Clermont-Ferrand</wicri:regionArea><placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region><region type="old region" nuts="2">Auvergne (région administrative)</region><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation><affiliation wicri:level="3"><nlm:aff id="I3">Occupational Medicine, Faculty of Medicine, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Occupational Medicine, Faculty of Medicine, F-63000, Clermont-Ferrand</wicri:regionArea><placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region><region type="old region" nuts="2">Auvergne (région administrative)</region><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author><author><name sortKey="Lac, Gerard" sort="Lac, Gerard" uniqKey="Lac G" first="Gérard" last="Lac">Gérard Lac</name><affiliation wicri:level="3"><nlm:aff id="I1">Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand</wicri:regionArea><placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region><region type="old region" nuts="2">Auvergne (région administrative)</region><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation></author><author><name sortKey="Courteix, Daniel" sort="Courteix, Daniel" uniqKey="Courteix D" first="Daniel" last="Courteix">Daniel Courteix</name><affiliation wicri:level="3"><nlm:aff id="I1">Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand</wicri:regionArea><placeName><region type="region" nuts="2">Auvergne-Rhône-Alpes</region><region type="old region" nuts="2">Auvergne (région administrative)</region><settlement type="city">Clermont-Ferrand</settlement></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="I6">School of Exercise Science, Australian Catholic University, Locked Bag 4115 Fitzroy MDC VIC 3165, , Australia</nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea>School of Exercise Science, Australian Catholic University, Locked Bag 4115 Fitzroy MDC VIC 3165, </wicri:regionArea><wicri:noRegion></wicri:noRegion></affiliation></author><author><name sortKey="Dore, Eric" sort="Dore, Eric" uniqKey="Dore E" first="Eric" last="Doré">Eric Doré</name><affiliation wicri:level="1"><nlm:aff id="I1">Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation></author><author><name sortKey="Chapier, Robert" sort="Chapier, Robert" uniqKey="Chapier R" first="Robert" last="Chapier">Robert Chapier</name><affiliation wicri:level="1"><nlm:aff id="I1">Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation></author><author><name sortKey="Roszyk, Laurence" sort="Roszyk, Laurence" uniqKey="Roszyk L" first="Laurence" last="Roszyk">Laurence Roszyk</name><affiliation wicri:level="1"><nlm:aff id="I5">Biochemistry, University Hospital (CHU) G. Montpied, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Biochemistry, University Hospital (CHU) G. Montpied, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation></author><author><name sortKey="Sapin, Vincent" sort="Sapin, Vincent" uniqKey="Sapin V" first="Vincent" last="Sapin">Vincent Sapin</name><affiliation wicri:level="1"><nlm:aff id="I5">Biochemistry, University Hospital (CHU) G. Montpied, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Biochemistry, University Hospital (CHU) G. Montpied, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation></author><author><name sortKey="Lesourd, Bruno" sort="Lesourd, Bruno" uniqKey="Lesourd B" first="Bruno" last="Lesourd">Bruno Lesourd</name><affiliation wicri:level="1"><nlm:aff id="I1">Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Clermont University, Blaise Pascal University, Laboratory of Metabolic Adaptations to Exercise in Physiological and Pathological conditions (AME2P, EA3533), BP 10448, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation><affiliation wicri:level="1"><nlm:aff id="I4">Geriatrics Departments, Faculty of Medicine, F-63000, Clermont-Ferrand, France</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>Geriatrics Departments, Faculty of Medicine, F-63000, Clermont-Ferrand</wicri:regionArea><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion><wicri:noRegion>63000, Clermont-Ferrand</wicri:noRegion></affiliation></author></analytic><series><title level="j">Nutrition Journal</title><idno type="eISSN">1475-2891</idno><imprint><date when="2012">2012</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><sec><title>Background</title><p>The recommended dietary allowance (RDA) for protein intake has been set at 1.0-1.3 g/kg/day for senior. To date, no consensus exists on the lower threshold intake (LTI = RDA/1.3) for the protein intake (PI) needed in senior patients ongoing both combined caloric restriction and physical activity treatment for metabolic syndrome. Considering that age, caloric restriction and exercise are three increasing factors of protein need, this study was dedicated to determine the minimal PI in this situation, through the determination of albuminemia that is the blood marker of protein homeostasis.</p></sec><sec><title>Methods</title><p>Twenty eight subjects (19 M, 9 F, 61.8 ± 6.5 years, BMI 33.4 ± 4.1 kg/m<sup>2</sup>) with metabolic syndrome completed a three-week residential programme (Day 0 to Day 21) controlled for nutrition (energy balance of −500 kcal/day) and physical activity (3.5 hours/day). Patients were randomly assigned in two groups: Normal-PI (NPI: 1.0 g/kg/day) and High-PI (HPI: 1.2 g/kg/day). Then, patients returned home and were followed for six months. Albuminemia was measured at D0, D21, D90 and D180.</p></sec><sec><title>Results</title><p>At baseline, PI was spontaneously 1.0 g/kg/day for both groups. Albuminemia was 40.6 g/l for NPI and 40.8 g/l for HPI. A marginal protein under-nutrition appeared in NPI with a decreased albuminemia at D90 below 35 g/l (34.3 versus 41.5 g/l for HPI, p < 0.05), whereas albuminemia remained stable in HPI.</p></sec><sec><title>Conclusion</title><p>During the treatment based on restricted diet and exercise in senior people with metabolic syndrome, the lower threshold intake for protein must be set at 1.2 g/kg/day to maintain blood protein homeostasis.</p></sec></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Alberti, Kg" uniqKey="Alberti K">KG Alberti</name></author><author><name sortKey="Zimmet, P" uniqKey="Zimmet P">P Zimmet</name></author><author><name sortKey="Shaw, J" uniqKey="Shaw J">J Shaw</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bassand, Jp" uniqKey="Bassand J">JP Bassand</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Laaksonen, De" uniqKey="Laaksonen D">DE Laaksonen</name></author><author><name sortKey="Lakka, Hm" uniqKey="Lakka H">HM Lakka</name></author><author><name sortKey="Niskanen, Lk" uniqKey="Niskanen L">LK Niskanen</name></author><author><name sortKey="Kaplan, Ga" uniqKey="Kaplan G">GA Kaplan</name></author><author><name sortKey="Salonen, Jt" uniqKey="Salonen J">JT Salonen</name></author><author><name sortKey="Lakka, Ta" uniqKey="Lakka T">TA Lakka</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ford, Es" uniqKey="Ford E">ES Ford</name></author><author><name sortKey="Giles, Wh" uniqKey="Giles W">WH Giles</name></author><author><name sortKey="Dietz, Wh" uniqKey="Dietz W">WH Dietz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rosenberg, Ih" uniqKey="Rosenberg I">IH Rosenberg</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hughes, Va" uniqKey="Hughes V">VA Hughes</name></author><author><name sortKey="Frontera, Wr" uniqKey="Frontera W">WR Frontera</name></author><author><name sortKey="Wood, M" uniqKey="Wood M">M Wood</name></author><author><name sortKey="Evans, Wj" uniqKey="Evans W">WJ Evans</name></author><author><name sortKey="Dallal, Ge" uniqKey="Dallal G">GE Dallal</name></author><author><name sortKey="Roubenoff, R" uniqKey="Roubenoff R">R Roubenoff</name></author><author><name sortKey="Fiatarone Singh, Ma" uniqKey="Fiatarone Singh M">MA Fiatarone Singh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Guillet, C" uniqKey="Guillet C">C Guillet</name></author><author><name sortKey="Prod Homme, M" uniqKey="Prod Homme M">M Prod'homme</name></author><author><name sortKey="Balage, M" uniqKey="Balage M">M Balage</name></author><author><name sortKey="Gachon, P" uniqKey="Gachon P">P Gachon</name></author><author><name sortKey="Giraudet, C" uniqKey="Giraudet C">C Giraudet</name></author><author><name sortKey="Morin, L" uniqKey="Morin L">L Morin</name></author><author><name sortKey="Grizard, J" uniqKey="Grizard J">J Grizard</name></author><author><name sortKey="Boirie, Y" uniqKey="Boirie Y">Y Boirie</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Hebuterne, X" uniqKey="Hebuterne X">X Hébuterne</name></author><author><name sortKey="Broussard, Jf" uniqKey="Broussard J">JF Broussard</name></author><author><name sortKey="Rampal, P" uniqKey="Rampal P">P Rampal</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Martin, A" uniqKey="Martin A">A Martin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Trumbo, P" uniqKey="Trumbo P">P Trumbo</name></author><author><name sortKey="Schlicker, S" uniqKey="Schlicker S">S Schlicker</name></author><author><name sortKey="Yates, Aa" uniqKey="Yates A">AA Yates</name></author><author><name sortKey="Poos, M" uniqKey="Poos M">M Poos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Paddon Jones, D" uniqKey="Paddon Jones D">D Paddon-Jones</name></author><author><name sortKey="Short, Kr" uniqKey="Short K">KR Short</name></author><author><name sortKey="Campbell, Ww" uniqKey="Campbell W">WW Campbell</name></author><author><name sortKey="Volpi, E" uniqKey="Volpi E">E Volpi</name></author><author><name sortKey="Wolfe, Rr" uniqKey="Wolfe R">RR Wolfe</name></author></analytic></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Zello, Ga" uniqKey="Zello G">GA Zello</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Evans, Wj" uniqKey="Evans W">WJ Evans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lucas, M" uniqKey="Lucas M">M Lucas</name></author><author><name sortKey="Heiss, Cj" uniqKey="Heiss C">CJ Heiss</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fuller, Mf" uniqKey="Fuller M">MF Fuller</name></author><author><name sortKey="Crofts, Rm" uniqKey="Crofts R">RM Crofts</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Munro, Hn" uniqKey="Munro H">HN Munro</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pellet, Pl" uniqKey="Pellet P">PL Pellet</name></author><author><name sortKey="Young, Vr" uniqKey="Young V">VR Young</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fry, Cs" uniqKey="Fry C">CS Fry</name></author><author><name sortKey="Rasmussen, Bb" uniqKey="Rasmussen B">BB Rasmussen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fouque, D" uniqKey="Fouque D">D Fouque</name></author><author><name sortKey="Guebre Egziabher, F" uniqKey="Guebre Egziabher F">F Guebre-Egziabher</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Larosa, Jc" uniqKey="Larosa J">JC Larosa</name></author><author><name sortKey="Fry, Ag" uniqKey="Fry A">AG Fry</name></author><author><name sortKey="Muesing, R" uniqKey="Muesing R">R Muesing</name></author><author><name sortKey="Rosing, Dr" uniqKey="Rosing D">DR Rosing</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lindeman, Rd" uniqKey="Lindeman R">RD Lindeman</name></author><author><name sortKey="Tobin, J" uniqKey="Tobin J">J Tobin</name></author><author><name sortKey="Shock, Nw" uniqKey="Shock N">NW Shock</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lindeman, Rd" uniqKey="Lindeman R">RD Lindeman</name></author><author><name sortKey="Tobin, Jd" uniqKey="Tobin J">JD Tobin</name></author><author><name sortKey="Shock, Nw" uniqKey="Shock N">NW Shock</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kasiske, Bl" uniqKey="Kasiske B">BL Kasiske</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Melchior, Jc" uniqKey="Melchior J">JC Melchior</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Koretz, Rl" uniqKey="Koretz R">RL Koretz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Black, Ae" uniqKey="Black A">AE Black</name></author><author><name sortKey="Coward, Wa" uniqKey="Coward W">WA Coward</name></author><author><name sortKey="Cole, Tj" uniqKey="Cole T">TJ Cole</name></author><author><name sortKey="Prentice, Am" uniqKey="Prentice A">AM Prentice</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ainsworth, Be" uniqKey="Ainsworth B">BE Ainsworth</name></author><author><name sortKey="Haskell, Wl" uniqKey="Haskell W">WL Haskell</name></author><author><name sortKey="Leon, As" uniqKey="Leon A">AS Leon</name></author><author><name sortKey="Jacobs, Dr" uniqKey="Jacobs D">DR Jacobs</name></author><author><name sortKey="Montoye, Hj" uniqKey="Montoye H">HJ Montoye</name></author><author><name sortKey="Sallis, Jf" uniqKey="Sallis J">JF Sallis</name></author><author><name sortKey="Paffenbarger, Rs" uniqKey="Paffenbarger R">RS Paffenbarger</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pannemans, Dl" uniqKey="Pannemans D">DL Pannemans</name></author><author><name sortKey="Westerterp, Kr" uniqKey="Westerterp K">KR Westerterp</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kamel, Eg" uniqKey="Kamel E">EG Kamel</name></author><author><name sortKey="Mcneill, G" uniqKey="Mcneill G">G McNeill</name></author><author><name sortKey="Van Wijk, Mc" uniqKey="Van Wijk M">MC Van Wijk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cockcroft, Dw" uniqKey="Cockcroft D">DW Cockcroft</name></author><author><name sortKey="Gault, Mh" uniqKey="Gault M">MH Gault</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Howell, Dc" uniqKey="Howell D">DC Howell</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Bonnefoy, M" uniqKey="Bonnefoy M">M Bonnefoy</name></author><author><name sortKey="Laville, M" uniqKey="Laville M">M Laville</name></author><author><name sortKey="Ecochard, R" uniqKey="Ecochard R">R Ecochard</name></author><author><name sortKey="Jusot, Jf" uniqKey="Jusot J">JF Jusot</name></author><author><name sortKey="Normand, S" uniqKey="Normand S">S Normand</name></author><author><name sortKey="Maillot, S" uniqKey="Maillot S">S Maillot</name></author><author><name sortKey="Lebreton, B" uniqKey="Lebreton B">B Lebreton</name></author><author><name sortKey="Jauffret, M" uniqKey="Jauffret M">M Jauffret</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Millward, Dj" uniqKey="Millward D">DJ Millward</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Chernoff, R" uniqKey="Chernoff R">R Chernoff</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Australie</li><li>France</li></country><region><li>Auvergne (région administrative)</li><li>Auvergne-Rhône-Alpes</li></region><settlement><li>Clermont-Ferrand</li></settlement></list><tree><country name="France"><region name="Auvergne-Rhône-Alpes"><name sortKey="Dutheil, Frederic" sort="Dutheil, Frederic" uniqKey="Dutheil F" first="Frédéric" last="Dutheil">Frédéric Dutheil</name></region><name sortKey="Chapier, Robert" sort="Chapier, Robert" uniqKey="Chapier R" first="Robert" last="Chapier">Robert Chapier</name><name sortKey="Courteix, Daniel" sort="Courteix, Daniel" uniqKey="Courteix D" first="Daniel" last="Courteix">Daniel Courteix</name><name sortKey="Dore, Eric" sort="Dore, Eric" uniqKey="Dore E" first="Eric" last="Doré">Eric Doré</name><name sortKey="Dutheil, Frederic" sort="Dutheil, Frederic" uniqKey="Dutheil F" first="Frédéric" last="Dutheil">Frédéric Dutheil</name><name sortKey="Dutheil, Frederic" sort="Dutheil, Frederic" uniqKey="Dutheil F" first="Frédéric" last="Dutheil">Frédéric Dutheil</name><name sortKey="Lac, Gerard" sort="Lac, Gerard" uniqKey="Lac G" first="Gérard" last="Lac">Gérard Lac</name><name sortKey="Lesourd, Bruno" sort="Lesourd, Bruno" uniqKey="Lesourd B" first="Bruno" last="Lesourd">Bruno Lesourd</name><name sortKey="Lesourd, Bruno" sort="Lesourd, Bruno" uniqKey="Lesourd B" first="Bruno" last="Lesourd">Bruno Lesourd</name><name sortKey="Roszyk, Laurence" sort="Roszyk, Laurence" uniqKey="Roszyk L" first="Laurence" last="Roszyk">Laurence Roszyk</name><name sortKey="Sapin, Vincent" sort="Sapin, Vincent" uniqKey="Sapin V" first="Vincent" last="Sapin">Vincent Sapin</name></country><country name="Australie"><noRegion><name sortKey="Courteix, Daniel" sort="Courteix, Daniel" uniqKey="Courteix D" first="Daniel" last="Courteix">Daniel Courteix</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005225 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 005225 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3502154
|texte= Treatment of Metabolic syndrome by combination of physical activity and diet needs an optimal protein intake: a randomized controlled trial
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:22985437" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |